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Listar por autor "López Lázaro, Miguel"
Mostrando ítems 1-20 de 59
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Artículo
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
Orta Vázquez, Manuel Luis; Calderón Montaño, José Manuel; Domínguez García, Inmaculada; Pastor Carrillo, Nuria María; Burgos Morón, Estefanía; López Lázaro, Miguel; Cortés, Felipe; Mateos Cordero, Santiago; Helleday, Thomas (Oxford University Press, 2013)5-Aza-2'-deoxycytidine (5-azadC) is a DNA methyltransferase (DNMT) inhibitor increasingly used in treatments of hematological ...
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Artículo
A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells
Calderón Montaño, José Manuel; Burgos Morón, Estefanía; Orta Vázquez, Manuel Luis; Mateos Cordero, Santiago; López Lázaro, Miguel (Georg Thieme Verlag, 2013)Recent evidence suggests that cardiac glycosides might be used for the treatment of cancer. The ornamental shrub Nerium ...
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Artículo
A local mechanism by which alcohol consumption causes cancer
López Lázaro, Miguel (2016)Epidemiological data indicate that 5.8% of cancer deaths world-wide are attributable to alcohol consumption. The risk of ...
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Artículo
A new view of carcinogenesis and an alternative approach to cancer therapy
López Lázaro, Miguel (2010) -
Patente. Invención
Actividad citotóxica de la fracción de acetato de etilo de un extracto obtenido de Viscum cruciatum Sieber
Martín Cordero, Carmen; Pedraza Cerbán, Mª Ángeles; Gálvez Peralta, Marina; López Lázaro, Miguel; Ayuso González, Mª Jesús (Oficina Española de Patentes y Marcas (OEPM), 2007-10-22)Actividad citotóxica de la fracción de acetato de etilo de un extracto obtenido de Viscum cruciatum Sieber. La presente ...
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Patente. Invención
Antagonistas de los receptores nk1 derivados de hidratos de carbono, metodo de obtencion y uso medico
Khiar El Wahabi, Noureddine; Fernández Fernández, Inmaculada; Recio Jiménez, Rocío; López Lázaro, Miguel; Calderon Montaño, Jose Manuel (Oficina Española de Patentes y Marcas (OEPM), 2017-09-27)Antagonistas de los receptores NK1 derivados de hidratos de carbono, método de obtención y uso médico. La presente ...
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Artículo
Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii
López Lázaro, Miguel; Palma de la Peña, Nieves; Pastor Carrillo, Nuria María; Martín Cordero, Carmen; Navarro, Eduardo; Cortés Benavides, Felipe; Ayuso, María Jesús; Toro Sainz, María Victoria (Georg Thieme Verlag, 2003)Recent research has shown the anticancer effects of digitalis compounds suggesting their possible use in medical oncology. ...
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Artículo
Artificial Diets Based on Selective Amino Acid Restriction versus Capecitabine in Mice with Metastatic Colon Cancer
Jiménez Alonso, Julio José; Guillén Mancina, Emilio; Calderón Montaño, José Manuel; Jiménez González, Víctor; Díaz Ortega, Patricia; Burgos Morón, Estefanía; López Lázaro, Miguel (MDPI, 2022)New therapies are needed to improve the low survival rates of patients with metastatic colon cancer. Evidence suggests ...
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Artículo
Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma
Jiménez Alonso, Julio José; Guillén Mancina, Emilio; Calderón Montaño, José Manuel; Jiménez González, Víctor; Díaz Ortega, Patricia; Burgos Morón, Estefanía; López Lázaro, Miguel (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Sulfur-containing amino acids methionine (Met), cysteine (Cys) and taurine (Tau) are common dietary constituents with ...
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Artificial Diets with Selective Restriction of Amino Acids and Very Low Levels of Lipids Induce Anticancer Activity in Mice with Metastatic Triple-Negative Breast Cancer
Guillén Mancina, Emilio; Jiménez Alonso, Julio José; Calderón Montaño, José Manuel; Jiménez González, Víctor; Díaz Ortega, Patricia; Burgos Morón, Estefanía; López Lázaro, Miguel (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Current treatments for patients with metastatic triple negative breast cancer (TNBC) are generally ineffective. This ...
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Trabajo Fin de Grado
Biología y terapia del retinoblastoma
Redondo Galán, Carmen (2017-07)El retinoblastoma es un tumor intraocular poco frecuente en la infancia que se produce en las células de la retina en ...
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Artículo
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity
Recio Jiménez, Rocío; Lerena Pérez, Patricia; Pozo Torres, Esther; Calderón Montaño, José Manuel; Burgos Morón, Estefanía; López Lázaro, Miguel; Valdivia Giménez, Victoria Esther; Pernia Leal, Manuel; Mouillac, Bernard; Organero, Juan Ángel; Khiar, Noureddine; Fernández Fernández, Inmaculada (American Chemical Society, 2021)NK1R antagonists, investigated for the treatment of several pathologies, have shown encouraging results in the treatment ...
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Artículo
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
Burgos Morón, Estefanía; Calderón Montaño, José Manuel; Orta Vázquez, Manuel Luis; Guillén Mancina, Emilio; Mateos Cordero, Santiago; López Lázaro, Miguel (MDPI AG, 2016)Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular ...
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Artículo
Chemo-protective activity and characterization of phenolic extracts from Corema album
León González, Antonio José; Mateos, Raquel; Ramos, Sonia; Martín, M. Ángeles; Sarriá, Beatriz; Martín Cordero, Carmen; López Lázaro, Miguel; Bravo, Laura; Goya, Luis (Elsevier, 2012)There is currently substantial interest in the cyto-protective effects of natural compounds against oxidative stress and ...
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Artículo
Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes
Carrasco Carrasco, Carlos Jesús; Montilla Ramos, Francisco Javier; Álvarez González, Eleuterio; Calderón Montaño, José Manuel; López Lázaro, Miguel; Galindo del Pozo, Agustín (Elsevier, 2022)Complexes Na3[Ag(NHCR)2], 2a-e and 2b’-c’, where NHCR is a N-heterocyclic carbene of the 2,2′-(1H-2λ3,3λ4-imidazole-1,3-diyl)dicarboxylate ...
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Artículo
Cholesterol levels affect the performance of aunps-decorated thermo-sensitive liposomes as nanocarriers for controlled doxorubicin delivery
García, Mónica C.; Naitlho, Nabila; Calderón Montaño, José Manuel; Drago, Estrella; Rueda Rueda, Manuela; Longhi, Marcela; Rabasco Álvarez, Antonio María; López Lázaro, Miguel; Prieto Dapena, Francisco; González Rodríguez, María Luisa (Multidisciplinary Digital Publishing Institute (MDPI), 2021)Stimulus-responsive liposomes (L) for triggering drug release to the target site are particularly useful in cancer therapy. ...
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Artículo
Comment on ‘Quiescence and γH2AX in neuroblastoma are regulated by Ouabain/Na,K-ATPase': ouabain and cáncer
Calderón Montaño, José Manuel; Burgos Morón, Estefanía; López Lázaro, Miguel (Nature Publishing Group, 2013) -
Artículo
Consumption of the Dietary Flavonoids Quercetin, Luteolin and Kaempferol and Overall Risk of Cancer - A Review and Meta-Analysis of the Epidemiological Data
López Lázaro, Miguel; Burgos Morón, Estefanía; Tena, J.D.; Sanz, I.; Sainz, J; Calderón Montaño, José Manuel (Biomedical Publisher, 2013)Numerous epidemiological and preclinical studies suggest that flavonoids may play an important role in the decreased risk ...
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Artículo
Curcumin as a DNA Topoisomerase II Poison
Martín Cordero, Carmen; López Lázaro, Miguel; Gálvez, Marina; Ayuso, Maria Jesús (Taylor & Francis Open Access, 2003)Curcumin, the major active component of the spice turmeric, is recognised as a safe compound with great potential for ...
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Artículo
Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L.
Berrougui, Hicham; López Lázaro, Miguel; Martín Cordero, Carmen; Mamouchi, Mohamed; Ettaib, Abdelkader; Herrera González, María Dolores (Natural Remedies Pvt Ltd, 2005)To study the cytotoxic activity of P. harmala. Materials and method: The alkaloids harmine and harmaline have been isolated ...